R-407C is an HFC refrigerant replacement for R-22 in positive displacement systems such as new or existing residential and commercial air-conditioners and heat pumps. R-407C offers similar performance to R-22 and can be used to retrofit existing R-22 air-conditioning systems. R-407C can also be used to replace R-502 for some existing medium-temperature applications with evaporator temperatures above +20°F (-7°C).